09 NovPorokeratosis Definition

One can make porokeratosis definition as a term used to refer to several dermatological disorders that affect the skin on various parts of the body. This condition is heritable and is characterized by abnormal clones of keratinocyte leading to production of lesions. The lesions are very irritating and also ugly to look at. Porokeratosis affect mostly the limbs and especially the legs. They are referred to as seed corns by most patients. Porokeratosis definition is usually not clear to many but it is a disorder of keratinisation that includes three autosomal dominant syndromes that occur separately. All these will show lesions with raised borders and the central part of the lesion has a furrow. To most people, the probability or the chance of one inheriting the gene from a parent to develop the disease is half.

For instance, porokeratosis of mibelli is characterized by lesions that are crater-like with raised borders. They appear on any part of the body but the palms and toes are mostly attacked. This is a good porokeratosis definition of this type of porokeratosis. The lesions will appear in groups arranged in lines or segments but others will come out as alone in the very early stages. This disease has been associated with females but when a male is faced with the disease, it is usually very serious.  It comes in the early ages of childhood and the lesions are proportional to age and size of the body.

Another porokeratosis definition is the one characterized by brownish red macules and is known as superficial actinic porokeratosis. This is triggered by sunlight and you will find lesions appearing on the body parts that are mostly exposed to the sun. The light skinned people, especially females, are common casualties of this condition. The lesions have sharply protruding borders and very itchy. Unlike the porokeratosis plantaris the lesions do not affect the palms and toes this time round but the rest of the body and do not have specific time to appear on the body. For porokeratosis plantaris, lesions come out during the early ages of the second decade of age.

During treatment of the mibelli form, dermatologists remove the underdeveloped lesions through a surgical operation. Another option is applying 5-fluorouracil on the affected areas for some time. Those who are affected by superficial actinic form should use sunscreen on their skin or avoid sunlight as much as possible. This is a dermatological condition that has proven to be incurable over the years.



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10 AugWhat Is Porokeratosis?

Porokeratosis is a disorder of keratinization or a skin disorder. The disease is widely known as a hereditary dermatitis; it runs down a family related line. Its main characteristic is the spreading of lesions on the body. The disease can affect any part of the body, and it mostly affects the adults. It is known to be common in male than in female.

It is normally caused by a defect (disorder) in the formation of skin because of immunosuppression, ultraviolet light exposure or radiation therapy. It happens when part of the skin tissues grow quickly and results to rising over the other part. They are 4 known types of Porokeratosis;

Porokeratosis of Mebelli (PM)

The skin disorder occurs as a single or a number of plaques centrally depressed with a marginated border. The only way to identify the disorder is by biopsy. This is a medical test which involves the removal of cells or tissues of a given affected body are to be examined.

It is benign; rarely would it develop to cancer. The lesions can be treated or removed by, cryotherapy, excision or the use of fluorouracil.

Disseminated Superficial Actinic Porokeratosis (DSAP)

It is the most common type of Porokeratosis. It is a non-contagious skin condition. This type of skin disorder is also hereditary; its cause is of genetic origin. Mainly affects the elderly. It mostly affects the body parts that are normally exposed to sunlight. It is known to affect women more than men.

Porokeratosis plantaris, Palmaris, et disseminate

It is a benign that mostly affects palms and soles but if not quickly treated, it may spread to other parts of the body. It is very rare as it is listed as a rare disease by the Office of Rare Diseases (ORD) and it occurs by gradual thickening of the skin on the palms and sole.

Linear Porokeratosis

It is also a rare disease as it is also listed as a rare disease but affects both male and female. The skin disorder is characterized by papules and plaques on the body which form a linear pattern. It may occur at birth or appear later at adult age. Just like the other types of Porokeratosis, Linear Porokeratosis has also been linked to be caused by genetic origin. It has been present mostly on monozygotic twins.

Though some types of this disease may be harmless at first, it is important to note that some may end up resulting to skin cancer. It is therefore recommended that you visit a dermatologist as soon as you suspect any of the above symptoms.


Recent Porokeratosis Articles:

Porokeratosis Plantaris Palmaris Et Disseminate (PPPD)

Disseminated Superficial Actinic Porokeratosis (DSAP)